I think most of the difference comes in the mix really. If you want to pan/add effects and things like that, you have more flexibility with stereo.. but I usually record only in mono.
mono, and it stays mono in mixing with sends to reverb/delay/exciters for a little pseudo stereo enhancement, depth and width.
unless you have a stereo mic or record in the various m/s matrix styles (including ms encoder/decoder plugs) then your recording in mono, you're just putting it onto a stereo channel.