you can always imported you own custom made sounds into Reason.. Dont feel limited to reason's stock sounds you can always tweak them and remember all sounds that in vst's also come in RAW . wav format...
I've had alot of my material on .Mtv, bet, radio, few commercial releases using nothing but reason.. its quite simple if you know how to work it you know how to work it.. its not harder to make a track in reason sound good compared to using a Multitrack recroder and vst, Au or rtas plugin,..
Can make the same caliber track using Dp4 + Sampletank that i can using reason(visa versa)..all depends on your sounds and what u can do with em
But Mixing is a diff story i would much rather mix in something such as dp, cubase(like D mentioned) Logic
I'll get at cha broussard