There's Receptor, Creamware Noah and Plugzilla
The specs in reverse order,
Plugzilla is cutting edge…
• Ships with over
300 plugins
• Run up to
eight plugins simultaneously
• Runs nearly any PC-based Windows or Linux VST plugin*, including VSTi instruments
• Built-in Real Time Analyzer (RTA) with selectable frequency resolution (1/3, 1/6, or 1/12 octave)
• High-performance processing: capable of running 8 channels of reverb
• Compliant with Steinberg VST version 2.3 and Linux Audio Developer’s Simple Plugin API (LADSPA)
•
Dual-machine architecture with extensive audio routing options
• Internal hard drive storage for thousands of plugins and presets
• Premiere plugins from PSPaudioware and Princeton Digital with more coming soon
Plugzilla has the professional features you need and expect…
• Easy-to-use interface
•
Eight balanced XLR analog inputs and outputs with failsafe relay protection
•
AES/EBU and S/PDIF digital I/O, BNC Word Clock
• 24-bit audio with sample rates up to 96kHz and latencies down to less than 2ms.
• +4/-10dBu operation
• Extensive audio metering and CPU monitoring
• 2 MIDI Ins and Outs for 32 MIDI channels, 1 hard MIDI Thru
• Fast MIDI response
• 2 1/4” TRS connectors for Footswitch control
• Automation via MIDI, Hot Knobs, Footswitches and USB
http://www.plugzilla.com/overview
Plugzilla has the features you will wonder how you ever lived without…
• Snapshot preset storage: Quickly save and load the entire state of Plugzilla in just two button presses.
• USB for external plugin and preset storage: Wherever you go, your plugins and presets go too.
• Ethernet for updating and installation: Update your software, plugins, and presets right over the Internet without ever needing an extra computer or monitor. Connect Plugzilla to your Windows PC and install new plugins and presets using the included PZView® software.
• Hot Knobs® parameter automation: Create custom parameter sets based on your workflow to control Plugzilla as well as other MIDI devices.
• SynthEdit shareware custom plugin creation tool: Have a unique need not currently available? Use SynthEdit to create it and Plugzilla to run it.
The Noah is from 2002 thus somewhat limited. 2 machines (not vst's but creamware plugs), Stereo I/O 44khz/32bit (unbalanced), ADAT/SPdif, USB, Wordclock and Midi I/O/T. Reason for the limited amount of machines is due to the fact that it shares its resources with fx and dynamic processing plugs (at zero latency!), 34 machines and with a stereo in makes a nice fx/dynamcis rack.
http://www.creamware.com/index.php?submenu=products&seite=products&lang=en
The muse enables up to 16 vst's, Stereo I/O (balanced) 96kHz/24bit, SPdif, ADAT, MIDI I/O/T, Mouse/VGA ports, 4xusb+plus front Ilok usb, Ethernet, High-Z input for Guitar.
http://www.museresearch.com/receptor_overview.php