Use the USB cable to connect to your PC, from the Oxygen. Open reason, go to the preferences under edit, and select MIDI from the drop down box. Use the drop down box to select your keyboard, and select the channel you will be recording to the sequencer. If you see a green check next to your keyboard name after its been selected its working. Then you can go to the advavced MIDI section. Choose your MIDI BUS options and the Remote control options, so you can use the sliders and knobs on your keyboard, if you hav them.